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Duke vs. Clemson prediction, odds: 2022 college basketball picks, Jan. 25 best bets from model on 49-36 run

The ninth-ranked Duke Blue Devils will look to stay red hot when they take on the Clemson Tigers in a key Atlantic Coast Conference matchup on Tuesday. The Blue Devils (15-3, 5-2), who have won three of four and eight of 10, are coming off a dominating 75-59 win over the Syracuse Orange on Saturday. The Tigers (11-8, 3-5) snapped a three-game losing skid on Saturday with a 75-48 thrashing of Pittsburgh. Since starting 4-0, Clemson is just 7-8 since Nov. 19.

The game from Cameron Indoor in Durham, N.C., is scheduled to tip off at 7 p.m. ET. Clemson is averaging 73.2 points per game, while Duke averages 82.6. The Blue Devils are 11-point favorites in the latest Duke vs. Clemson odds from Caesars Sportsbook, while the over-under for total points scored is set at 145.5. Before making any Clemson vs. Duke picks, be sure to check out the college basketball predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. It enters Week 12 of the season with a 49-36 record on all top-rated college basketball picks, returning almost $700. Over the past five-plus years, the proprietary computer model has generated an impressive profit of $2,800 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Duke vs. Clemson, and just locked in its picks and CBB predictions. You can visit SportsLine now to see the model’s picks. Here are the college basketball odds and betting lines for Clemson vs. Duke:

  • Duke vs. Clemson spread: Duke -11
  • Duke vs. Clemson over-under: 145.5 points
  • Duke vs. Clemson money line: Duke -800, Clemson +550
  • CLEM: The Tigers are 7-2 against the spread in their last nine games after allowing fewer than 50 points in their previous game
  • DUKE: The Blue Devils are 4-0 ATS in their last four home games against a team with a losing road record

Featured Game | Duke Blue Devils vs. Clemson Tigers

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Why Duke can cover 

Freshman guard Trevor Keels could miss the game with a lower leg injury, but sophomore guard Jeremy Roach could step up to help fill the void. Roach did just that on Saturday when he made his first start in four games against Syracuse and recorded a career-high nine assists with just one turnover in 28 minutes. Over the last four games, he has accounted for 19 assists and two turnovers. He ranks third in the ACC in assist-to-turnover ratio (2.58), joining teammates Keels (2.35, fourth) and Wendell Moore Jr. (2.21, sixth) in the ACC’s top 10.

Sophomore center Mark Williams has reached double figures in each of the last three games and averages 9.9 points per game. Williams is also averaging 6.7 rebounds and 3.3 blocks per game. He was dominant in the win over North Carolina State on Jan. 15 with a season-high 19 points on 9 of 12 shooting with 11 rebounds and a career-high eight blocked shots. The eight blocks were the most by a Duke player since Sheldon Williams had eight against Virginia on Jan. 28, 2006.

Why Clemson can cover

The Tigers have four players averaging double-digit scoring, led by sophomore forward PJ Hall. Hall has scored in double figures in each of the last 18 games, including a pair of double-doubles. In a loss at Syracuse last week, Hall scored 19 points and grabbed 11 rebounds. For the season, he is averaging 14.8 points, 5.8 rebounds, 1.6 assists and 1.1 blocks per game. He is hitting 49.3 percent of his field goals and 74.2 percent of his free throws.

Also leading Clemson is junior guard Al-Amir Dawes, who averages 11.6 points, 3.1 rebounds and 2.2 assists. He is hitting 41.7 percent of his field goals, including a blistering 41 percent of his 3-pointers, and 86.7 percent of his free throws. Dawes is coming off a 19-point effort in Saturday’s win against Pittsburgh, and has reached double-figure scoring in 10 games, including three of the last five. His best game was a 21-point performance in a 64-53 season-opening win over Presbyterian on Nov. 9.

How to make Clemson vs. Duke picks

SportsLine’s model is leaning over on the total, projecting 147 combined points. It has also generated an against-the-spread pick that cashes in well over 50 percent of simulations. You can only get the model’s picks at SportsLine

So who wins Duke vs. Clemson? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up $2,800 on its top-rated college basketball picks the last five years, and find out.

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