An interleague play matchup involves the Baltimore Orioles (13-18) going on the road to face the St. Louis Cardinals (17-13) on Thursday afternoon. These teams split the first two matchups of the series with St. Louis coming out on top 10-1 on Wednesday. This win snapped the Cardinals’ three-game losing streak. On the flip side, Baltimore just had its three-game win streak halted. Lefty Steven Matz (3-2, 7.01 ERA) is starting for St. Louis, while Baltimore will send righty Bryan Baker (1-1, 5.40 ERA) to the hill.
First pitch is set for 1:15 p.m. ET. Caesars Sportsbook lists St. Louis as the -210 money-line favorite (risk $210 to win $100) in the latest Orioles vs. Cardinals odds. The over-under for total runs expected is 8.5, up half a run from the opening line. Before making any Cardinals vs. Orioles picks, you need to check out the MLB predictions and betting advice from SportsLine’s advanced computer simulation model.
The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a sizzling start to the 2022 season. It’s on a 31-19 roll on top-rated MLB money-line picks through five weeks, returning almost $800 for $100 players. Anyone following it has seen huge returns.
Now, the model has set its sights on Cardinals vs. Orioles, and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Now, here are several MLB odds and betting lines for Orioles vs. Cardinals:
- Cardinals vs. Orioles money line: Cardinals -210, Orioles +180
- Cardinals vs. Orioles over-under: 8.5 runs
- Cardinals vs. Orioles run line: Cardinals -1.5 (+105)
- BAL: Has returned -8 on the money line this year
- STL: Has returned +95 on the money line this year
Featured Game | St. Louis Cardinals vs. Baltimore Orioles
Why you should back the Cardinals
Third baseman Nolan Arenado has been a constant force on both sides of the game for St. Louis. Arenado is rangy in the corner and throws the ball with accuracy across the diamond. The six-time All-Star makes solid contact due to his excellent hands with run-producing qualities. Arenado is leading the team in batting average (.315), home runs (7) and RBI (25). In his last game, he went 1-for-4 with a double and one RBI.
Second baseman Tommy Edman plays the game with outstanding instincts at the plate or in the field. Edman is a patient switch-hitter whose able to spray the ball across the yard with his compact swing. The 2021 Gold Glove Winner can steal for a few bases with his solid speed. Edman has a batting average of .286 with three homers and 16 RBs.
Why you should back the Orioles
Right fielder Anthony Santander is a nice spark in the lineup for Baltimore. Santander has some power, but owns good pitch recognition, drawing his fair share of walks. The 27-year-old has good athleticism with a solid throwing arm from the outfield. Santander has three homers and 13 RBI with a batting average of .253. On May 10, he went 3-for-5 with a double.
Designated hitter Trey Mancini is a very disciplined hitter. Mancini is patient at the plate and looks for the right pitch to turn on. The 2021 AL Comeback Player of the Year can smack the ball into any gap on the field. Mancini has a batting average of .278 with one home run and 11 runs batted in. He’s recorded a hit in five straight games.
How to make Orioles vs. Cardinals picks
SportsLine’s model is leaning over on the total, projecting 9.4 combined runs. It also says one side of the money line has all the value. You can only get the model’s MLB picks at SportsLine.
So who wins Cardinals vs. Orioles? And which side has all the value? Visit SportsLine now to see which side of the money line you need to jump on Thursday, all from the model that has crushed its MLB picks, and find out.