The Chicago White Sox visit the Cleveland Guardians to get the Tuesday MLB schedule underway. The AL Central rivals begin a doubleheader with an afternoon tilt at Progressive Field. The contest is a makeup game after a postponement in April, and it serves as the second game of a four-game series this week. Cleveland enters at 42-42, while Chicago is 41-44 this season. Shane Bieber (3-5, 3.44 ERA) is on the hill for Cleveland, while Chicago will start Davis Martin in a matchup of righties.
Caesars Sportsbook lists Cleveland as the -160 money-line favorite (risk $160 to win $100) for this 1:10 p.m. ET first pitch. The total number of runs Vegas thinks will be scored, or the over-under, is eight in the latest White Sox vs. Guardians odds. Before making any Guardians vs. White Sox picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.
The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 275-236 on top-rated MLB money-line picks since the start of the 2021 season, returning over $400 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.
Now, the model has set its sights on White Sox vs. Guardians, and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Here are several MLB odds and betting lines for Guardians vs. White Sox:
- White Sox vs. Guardians money line: Guardians -160, White Sox +135
- White Sox vs. Guardians over-under: 8 runs
- White Sox vs. Guardians run line: Guardians -1.5 (+130)
- CWS: The White Sox are 23-18 in day games
- CLE: The Guardians are 23-22 in day games
- White Sox vs. Guardians picks: See picks at SportsLine
Featured Game | Cleveland Guardians vs. Chicago White Sox
Why you should back the White Sox
Chicago’s offense is capable of big things. The White Sox are No. 3 in the American League in hits this season, and Chicago has a strong .254 batting average as a team. Chicago avoids strikeouts at an impressive rate, posting the fourth-fewest strikeouts in the AL, and Tim Anderson is a true standout.
The veteran shortstop was selected as the All-Star starter for the AL, and he is a former batting champion who boasts a .317 batting average and only a 13.2 percent strikeout rate in 2022. Anderson is flanked by Jose Abreu, a former AL MVP, and he has a .379 on-base percentage and a .461 slugging percentage this season. Chicago is deep and talented, and the White Sox are also facing a Cleveland team that is just 6-14 in the last 20 games.
Why you should back the Guardians
The Guardians deploy a highly effective offense. No team in the American League strikes out less than Cleveland, with the No. 1 strikeout rate in the league at 18.6 percent. The Guardians are also in the top five of the AL in batting average and doubles, with top-four marks in triples (16) and stolen bases (53). In the middle of it all is Jose Ramirez, and the veteran third baseman was just selected to his fourth All-Star Game.
Ramirez leads the AL in doubles (29) and runs batted in (66) this season, blasting 17 home runs and posting a .573 slugging percentage. Ramirez also has more walks than strikeouts in 2022, serving as a clear representation of his elite approach at the plate. Cleveland also has the edge on the mound behind former Cy Young winner Bieber and his 3.44 ERA this season, setting the stage for a strong overall projection in the opener.
How to make Guardians vs. White Sox picks
SportsLine’s model is leaning over on the total, projecting 8.2 combined runs. It also says one side of the money line has all the value. You can only get the model’s MLB picks at SportsLine.
So who wins White Sox vs. Guardians? And which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.