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Week 3 NFL picks, odds, 2022 best bets from advanced model: This 5-way football parlay returns 25-1

Two of the top quarterbacks of all-time will go head to head when Tom Brady and the Tampa Bay Buccaneers host Aaron Rodgers and the Green Bay Packers during the Week 3 NFL schedule. A three-time league MVP, Brady has helped get Tampa Bay off to a 2-0 start after returning from a brief retirement. Rodgers, who won his fourth NFL MVP Award last season, led the Packers to a convincing win against Chicago last Sunday after the team dropped its opener at Minnesota. The Buccaneers are 2.5-point favorites in the latest Week 3 NFL odds at Caesars Sportsbook. Other Week 3 NFL spreads include Buffalo as a 5.5-point favorite against Miami and New England as a 3-point underdog against Baltimore. Which Week 3 NFL lines should you target with your Week 3 NFL bets? Before you make any Week 3 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2022 NFL season on an incredible 139-102 run on top-rated NFL picks that dates back to the 2017 season.  

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 3. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 3 NFL picks at SportsLine

Top Week 3 NFL picks

After simulating every game 10,000 times, the model is high on the Cincinnati Bengals (-4.5) to win and cover against the New York Jets on Sunday. While Cincinnati has yet to win this year, it showed an ability to battle back in both of its losses. The reigning AFC champion trailed by 14 points in each contest, but rallied to forge ties before losing on field goals as time expired in overtime against Pittsburgh in its season-opener and the fourth quarter at Dallas last week.

The Jets were dominated at home by Baltimore in Week 1 and would have suffered their second straight double-digit loss this past Sunday if not for a miraculous comeback with less than two minutes remaining at Cleveland. The Bengals will try to get in the win column for the first time this season and avenge last season’s disappointing loss at New York. The model has Cincinnati covering the spread almost 60% of the time. See which other NFL parlay picks to make here.

How to make Week 3 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including backing a shocking team even though they were dominated last week. You can only see the model’s NFL Week 3 best bets and parlay at SportsLine

What are the model’s top Week 3 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 3 NFL best bets from a model on a 139-102 run on its top-rated picks, and find out.

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