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Houston vs. Tulane prediction, odds, spread: 2022 Week 5 college football picks, best bets from proven model

The Houston Cougars‘ quest to win the American Athletic Conference title begins when they host the Tulane Green Wave in the teams’ conference opener on Friday at TDECU Stadium in Houston. The preseason favorite to win the AAC, the Cougars (2-2) lost to Cincinnati in last season’s conference championship game. They have not won the AAC title since 2015. Meanwhile the Green Wave (3-1), who are coming off their first loss of the season, have won only one conference title since 1949 (the Conference USA title in ’98). They were picked to finish seventh in the 11-team AAC. 

Kickoff is 7 p.m. ET. The Cougars are 2.5-point favorites in the latest Houston vs. Tulane odds from Caesars Sportsbook, while the over/under for total points scored is 54.5. Before making any Tulane vs. Houston picks or college football predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed the model has seen huge returns.

Now the model has dialed in on Houston vs. Tulane and just revealed its coveted picks and predictions. You can head to SportsLine now to see all of the model’s college football picks. Now, here are the college football odds and trends for Tulane vs. Houston:  

  • Houston vs. Tulane spread: Cougars -2.5 
  • Houston vs. Tulane Over/Under: 54.5 points 
  • Houston vs. Tulane money line: Cougars -145, Green Wave +122 
  • HOU: Cougars lead the nation in net punting (46.3 yards per game) 
  • TUL: Green Wave lead the FBS in passing defense (102.5 yards per game) 
  • Houston vs. Tulane picks: See picks here

Featured Game | Houston Cougars vs. Tulane Green Wave

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Why Houston can cover

Houston has dominated the series between the teams. The Cougars have won 15 of the last 18 meetings, including the last two by a combined score of 89-53. Over their last 10 games against Tulane, they are averaging 39.4 points per game, outscoring the Green Wave 394-218. Houston is 8-1 in its last nine games at home against Tulane, including a 3-1 mark at TDECU Stadium.

In addition, running back Ta’Zhawn Henry is a versatile threat out of the backfield. A 5-foot-7, 180-pound senior, Henry rushed for 112 yards last week against Rice, surpassing the 100-yard mark for the third time in his career. Two weeks ago against Kansas, he became the first Houston running back to have 100 yards receiving in a game since October 2012.

Why Tulane can cover

Tulane has been stingy on defense this season. The Green Wave lead the country in passing defense (102.5 yards per game) and rank fourth in total defense (228.8). Earlier this season they limited Alcorn State to 109 total yards, including just 49 through the air, in a 52-0 victory.

In addition, Tulane already has pulled off a big road upset this season. On Sept. 17, the Green Wave knocked off Kansas State, 17-10, in Manhattan, Kan. The Wildcats, who are now ranked No. 25 in the country, were held to 1-of-5 on fourth down attempts in that game.

How to make Houston vs. Tulane picks

SportsLine’s model is leaning Over on the point total, projecting the teams to combine for 63 points. It also has an against-the-spread pick that cashes in almost 60% of simulations. You can see the model’s Tulane vs. Houston pick only at SportsLine.

So who wins Houston vs. Tulane? And which side is covering almost 60% of the time? Visit SportsLine now to see which side of the Tulane vs. Houston spread to jump on, all from the advanced model that is up more than $3,100 on top-rated picks, and find out.

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