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NFL Week 5 injuries: Jonathan Taylor, Shaquille Leonard ruled out for Colts ahead of Thursday game at Broncos

We are four weeks through the 2022 NFL regular season, and several clubs are dealing with impactful injuries. Just look at the quarterback issues around the league: The Dallas Cowboys still haven’t returned Dak Prescott after he suffered a thumb injury in the season opener, Mac Jones of the New England Patriots may miss his second game of the season due to a high ankle sprain and then there are questions around New York Giants quarterback Daniel Jones‘ ankle injury.

With the amount of injuries around the league, sometimes it’s hard to keep up. We at CBSSports.com are here for you to provide you with all the injury information you could possibly crave. Below, we will break down the midweek injury reports, and the final injury report for Thursday night’s matchup between the Indianapolis Colts and Denver Broncos.

All odds courtesy of Caesars Sportsbook.

Indianapolis Colts at Denver Broncos (-3)

The Colts are banged-up and will be missing several starters on a short week. The biggest name of course is the star running back, Taylor. He’s missed just one game in his NFL career, and that was due to his placement on the COVID-19 list back in 2020. Indy’s offense will have to operate differently without him in the lineup. On defense, the Colts will be without Blackmon, Leonard and Lewis. Leonard just made his 2022 debut last week against the Titans, but suffered a head/face injury. All four Colts players who were ruled out for Thursday night did not practice at all this week. 

Cleveland, Phillips and Turner were each limited participants throughout the week for Denver. The Broncos will have Russell Wilson (shoulder) and Melvin Gordon (neck) for Thursday night’s game after both players were listed as full participants on Wednesday’s injury report. 

New York Giants at Green Bay Packers (-8) (London)

Analysis to come.

Miami Dolphins (-3) at New York Jets

Zach Wilson was one of three Jets players who were limited at the start of the week. Wilson was listed with an ankle injury after making his season debut during this past Sunday’s win over the Steelers. Offensive lineman Max Mitchell (knee) and linebacker Quincy Williams (ankle) did not practice on Wednesday, while running back Breece Hall (knee) and linebacker Marcell Harris (neck) were limited. 

As expected, Tua Tagovailoa did not practice Wednesday as he continues to recover from his concussion sustained during last Thursday’s loss in Cincinnati. Cornerback Xavien Howard (groins) and receiver Jaylen Waddle (groin) were two other notable Dolphins players who also did not practice on Wednesday. 

Tennessee Titans (-2.5) at Washington Commanders

Linebackers Ola Adeniyi (neck), Bud Dupree (hip) and rookie wideout Treylon Burks (toe) were among the five Titans players that did not practice on Wednesday. Linebacker Monty Rice returned to practice on Wednesday, thus beginning his 21-day window to be activated to the 53-man roster. Rice has been recovering from a season-ending injury that was sustained during the 2021 season. 

Receiver Curtis Samuel (illness) was one of five Commanders players that did not practice on Wednesday. Running back Brian Robinson returned to practice Wednesday. Robinson has been recovering from two gunshot wounds to his lower body as the victim of an attempted robbery in late August. Robinson was placed on the non-football injury list on Sept. 1, which led to him being sidelined for the season’s first four games. 

Los Angeles Chargers (-3) at Cleveland Browns

Analysis to come.

Pittsburgh Steelers at Buffalo Bills (-14)

The Steelers are dealing with multiple injuries on defense — especially in the secondary. Cornerback Ahkello Witherspoon (hamstring), safety Terrell Edmunds (concussion) and safety Minkah Fitzpatrick (knee) did not practice on Wednesday, while cornerback Cam Sutton (groin/hamstring), cornerback Levi Wallace (foot), defensive lineman Chris Wormley (ankle) and defensive tackle Cameron Heyward (ankle/elbow) were limited participants. 

The Bills were missing several important players on Wednesday, as cornerback Christian Benford (hand), wide receiver Jamison Crowder (ankle), linebacker Tremaine Edmunds (hamstring), tight end Dawson Knox (foot/hamstring), wide receiver Jake Kumerow (ankle) and wide receiver Isaiah McKenzie (concussion) did not participate. Center Mitch Morse (elbow), offensive tackle Justin Murray (foot) and defensive tackle Jordan Phillips (hamstring) were limited participants. In good news, wide receiver Gabe Davis was a full participant with his ankle injury. 

Atlanta Falcons at Tampa Bay Buccaneers (-8.5)

Analysis to come.

Seattle Seahawks at New Orleans Saints (-5.5)

Analysis to come.

Houston Texans at Jacksonville Jaguars (-7)

Analysis to come.

Chicago Bears at Minnesota Vikings (-7)

Analysis to come.

Detroit Lions at New England Patriots (-3)

Analysis to come.

San Francisco 49ers (-6.5) at Carolina Panthers

The Panthers had a few players miss practice on Wednesday, as wide receiver Laviska Shenault Jr. sat out with a hamstring injury, cornerback Stantley Thomas-Oliver was out with a thigh issue and safety Xavier Woods sat with a hamstring injury. Star linebacker Frankie Luvu was a limited participant with a shoulder injury. 

Philadelphia Eagles (-5) at Arizona Cardinals

Analysis to come.

Dallas Cowboys at Los Angeles Rams (-4.5)

Analysis to come.

Cincinnati Bengals at Baltimore Ravens (-3)

Analysis to come.

Las Vegas Raiders at Kansas City Chiefs (-7)

Analysis to come.

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