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The Thanksgiving holiday is in the rearview mirror and just six weeks remain in the 2023 regular season, which means we’re about to embark on a mad dash towards the playoffs. That begins in Week 13, where the NFL boasts a number of huge matchups, including what could be an NFC Championship preview between the 49ers and Eagles.
As we do every week, we’ve collected all of the best picks and gambling content from CBSSports.com and SportsLine and put them in one place, so you can get picks against the spread from our CBS Sports experts as well as additional feature content for each game, including plays from top SportsLine experts and the SportsLine Projection Model, best bets from our staff, survivor picks and more. Ready? Let’s jump in.
All NFL odds via SportsLine consensus odds.
Which picks can you make with confidence in Week 13? And which Super Bowl contender goes down hard? Visit SportsLine, as its incredible model simulates every NFL game 10,000 times and is up well over $7,000 for $100 players on top-rated NFL picks since its inception.
Colts at Titans
Time: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Colts -2, O/U 44.5
Featured Game | Tennessee Titans vs. Indianapolis Colts
“Tennessee is 4-7 and largely an afterthought in a crowded AFC playoff hunt, especially with the other three teams in the AFC South sitting above .500. But quietly — very quietly even — the Titans are undefeated at home this year, beating the Chargers, Bengals, Falcons and Panthers in Nashville for their quartet of wins this season. They’ve got three other one-score losses this year; Tennessee’s not that far from being in the mix for the postseason. That’s how Mike Vrabel rolls, even with a rookie quarterback under center and a weakened roster. Derrick Henry absolutely destroys division opponents, especially late in the year, and this home game against a turnover-prone Gardner Minshew feels like a spot where he could find the end zone multiple times again. The Colts are gettable on the ground, having given up a bunch of yards to bad running teams over the last month or so. Henry might eat here.” — CBS Sports senior writer and “Pick Six NFL” podcast host Will Brinson on why he likes Titans +1.5 as one of his best bets for Week 13. To see the rest, click here.
Chargers at Patriots
Time: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Chargers -5.5, O/U 42.5
Featured Game | New England Patriots vs. Los Angeles Chargers
“This is a long trip for a Chargers team that has underachieved in a big way. But the Patriots have been even worse. At least the Chargers have a capable quarterback. Even the woeful Chargers pass defense won’t wake up the New England offense. The Chargers win it.” — CBS Sports senior NFL analyst Pete Prisco on why he likes the Chargers to beat the Patriots, 23-10. To see all of his Week 13 picks, click here.
Lions at Saints
Time: Sunday, 1 p.m. ET (FOX), stream on fubo (try for free)
Open: Lions -3, O/U 44.5
Featured Game | New Orleans Saints vs. Detroit Lions
The SportsLine Projection Model, which simulates every NFL game 10,000 times, enters Week 13 of the 2023 NFL season on an incredible 175-126 run on top-rated NFL picks that dates back to the 2017 season. That makes this the perfect tool to utilize for survivor pools. We can tell you the model is shying away from the 8-3 Lions even though they are four-point road favorites over the 5-6 Saints. Detroit suddenly has a problem with taking care of the football, as it has 10 giveaways over its past four games after having just seven turnovers over its first seven games. Forcing turnovers is what New Orleans does best, as its 20 takeaways are fourth-most in the NFL
However, the model is backing a team coming off back-to-back wins versus a Week 13 opponent mired in a losing streak! To see which team that is, go check out SportsLine.
“The Lions are coming off a bad home loss to the Packers, while the Saints are coming off a road loss to the Falcons. The Lions defense has become a major problem as of late. I look for Derek Carr to play well here as the Saints win a shootout against the Lions.” — CBS Sports senior NFL analyst Pete Prisco on why he likes New Orleans to pull off the upset and beat the Lions, 32-30. To see the rest of his Week 13 picks, click here.
Falcons at Jets
Time: Sunday, 1 p.m. ET (FOX), stream on fubo (try for free)
Open: Falcons -2.5, O/U 35.5
Featured Game | New York Jets vs. Atlanta Falcons
“I hope Aaron Rodgers isn’t bringing some kind of weird juju with him as he returns to practice as a limited participant. I’m sure the team is excited he’s back, but that team hasn’t been very good. Tim Boyle didn’t look like an upgrade over Zach Wilson, and who knows how much longer this talented defense can continue to shoulder the load. It felt like things fell apart a bit last week against the Miami Dolphins. As for the Falcons, they are back on top in the NFC South after defeating the New Orleans Saints. Jessie Bates III had an epic 90-yard pick-six, and Bijan Robinson went off for 123 total yards and two touchdowns. I’m going to trust that Arthur Smith continues to lean on his star rookie, and the defense can outplay Boyle.” — CBS Sports NFL writer Jordan Dajani explains why he is laying the points with Atlanta against the Jets. To see the rest of his Week 13 picks, click here.
Cardinals at Steelers
Time: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Steelers -6.5, O/U 40.5
“The Steelers seemed to find something on offense last week after the coordinator change, while the Cardinals went backward on offense last week in a loss to the Rams. The Steelers defense will again present a challenge for Kyler Murray and he will struggle. Kenny Pickett will be good enough to win it.” — CBS Sports senior NFL analyst Pete Prisco on why he likes the Steelers to clear the 5.5-point spread and beat the Cardinals, 24-13. To see all of his picks for Week 13, click here.
Dolphins at Commanders
Time: Sunday, 1 p.m. ET (FOX), stream on fubo (try for free)
Open: Dolphins -9, O/U 49
Featured Game | Washington Commanders vs. Miami Dolphins
“After a week that was dominated by favorites, some dogs are bound to pull through, and this game between the Dolphins and Commanders feels like one that could surprise some folks. While I’m not predicting the full-blown upset, I do think Washington covers. The Commanders are playing in their first game since firing DC Jack Del Rio, and Ron Rivera is set to take over the defensive play-calling duties. That should give the unit a small boost, but we’re more looking at the Commanders offense to keep us within the number. Sam Howell has shown flashes this season and leads the NFL in completions, attempts and passing yards. They have the skill position players capable of putting up points, and they won’t have to deal with pass rusher Jaelan Phillips throwing Howell to the turf after he suffered an Achilles injury last week. The Commanders are also 9-3-2 ATS in their past 14 games as underdogs and 5-1-1 ATS in their last seven where they are two-possession underdogs.” — CBS Sports NFL writer Tyler Sullivan on why he likes the Commanders to cover against Miami. To see all of his Week 13 picks, click here.
Broncos at Texans
Time: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Texans -3, O/U 45
Featured Game | Houston Texans vs. Denver Broncos
“This is a much different matchup for the Broncos, who have been thriving off turnovers during their last four games. The Texans have the second lowest interception rate on the season (behind the Broncos themselves), and they went back to avoiding any turnovers last week after posting three in two straight weeks. But they’ve also had trouble pulling away from teams in recent weeks, with their only win by more than three points in their last five matchups being a five-point win over a bad Cardinals team at home. Their defense is 24th in yards per play and 28th in yards per pass, and the Broncos should be able to score on this unit with Russell Wilson playing well, especially as they managed three drives of 70-plus yards against the elite Cleveland defense a week ago. The Broncos defense may also have a little easier of a time with Tytus Howard missing from the offensive line and the Texans dealing with multiple injuries in their receiving corps. I believe this line should be on the other side of 3, so I’m happy getting the hook here.”
R.J. White has been SportsLine’s No. 1 NFL against-the-spread expert over the last six years, going 535-450-30 against the spread to put him up more than 35 units on those picks at SportsLine since 2017. He has also delivered a 56.5% hit rate on my Vegas contest picks over the last eight seasons, which is what he’s circling above with Broncos +3.5. To see the rest of his Vegas contest picks, go check out SportsLine.
“The Broncos currently have the longest winning streak in the NFL, and a big reason for that is because their defense is forcing turnovers at a rate that doesn’t even seem possible. Over the past five weeks, the Broncos have forced 16 turnovers, which is crazy, when you consider that there are 18 teams that haven’t even forced 16 turnovers for the ENTIRE SEASON. And now, the Broncos will get to face a quarterback in C.J. Stroud, who has turned the ball over six times over the past three weeks (four interceptions and two lost fumbles).
“Although Stroud has been making some mistakes, you know who hasn’t? Russell F’ing Wilson. Heading into the 2023 season, it was looking like the Broncos had made the worst trade in the history of football by acquiring Wilson, but suddenly, they’re not the laughing stock of the league anymore. Not only is Wilson playing much better this season, but he’s been nearly unstoppable in the red zone AND on both third and fourth down.
“I guess what I’m trying to say here is that Stroud is going to turn the ball over multiple times, Wilson is going to throw multiple touchdown passes in the red zone and the Broncos are going to sneak out of Houston with a win.” — CBS Sports NFL writer John Breech on why he has the Broncos beating the Texans in Houston, 23-20. To see all of his Week 13 picks, click here.
Panthers at Buccaneers
Time: Sunday, 4:05 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Buccaneers -6, O/U 38.5
Featured Game | Tampa Bay Buccaneers vs. Carolina Panthers
“I’m not sure if you’ve heard, but things are not going well for the Panthers. With the firing of Frank Reich, they became the first team in NFL history to have three midseason head coach firings in a five-season span. They have the worst record in the NFL at 1-10 and don’t own their 2024 first-round pick to help in the rebuild.
“I believe firings can spark teams, like we saw with the Pittsburgh Steelers last week, but what is there to spark in Carolina? Rookie quarterback Bryce Young is struggling, his offensive line is one of the worst in the league and getting worse with each week, and then the defense is banged up.
“I don’t think the Buccaneers are contenders, but I do like Mike Evans, who caught six passes for 70 yards and two touchdowns last week against the Indianapolis Colts. The last time he played the Panthers, Evans exploded for 207 yards and three touchdowns! The Bucs are 7-4 ATS this season, and 5-1 ATS vs. the Panthers in their last six meetings. I’ll take the Bucs with the number under six points.” — CBS Sports NFL writer Jordan Dajani on why he likes the Buccaneers -5.5 against the Panthers. To see all of his picks for Week 13, click here.
Browns at Rams
Time: Sunday, 4:25 p.m. ET (FOX), stream on fubo (try for free)
Open: Rams -3.5, O/U 38.5
Featured Game | Los Angeles Rams vs. Cleveland Browns
“Don’t look now but the Rams are starting to get into a bit of a groove. They’ve won two straight and are coming off scoring a season-best 37 points against Arizona. Matthew Stafford has looked sharp over that stretch and the offense just welcomed back Kyren Williams, who adds an explosive figure in their backfield. Simply put, the arrow is pointing up in Los Angeles. Meanwhile, the same can’t be said for Cleveland, despite its 7-4 record. Dorian Thompson-Robinson left last week’s game with a concussion, further sending the QB position into question. Also, Myles Garrett was spotted in a sling after last week’s loss to Denver, signaling that he won’t be 100% for this game, either. The Browns defense is allowing 29.6 points per game on the road this season, which is a bad trend against a suddenly hot Rams unit.” — CBS Sports NFL writer Tyler Sullivan on why he likes the Rams to cover against Cleveland. To see all of his Week 13 picks, click here.
49ers at Eagles
Time: Sunday, 4:25 p.m. ET (FOX), stream on fubo (try for free)
Open: 49ers -1, O/U 46.5
Featured Game | Philadelphia Eagles vs. San Francisco 49ers
“The thing about the Eagles is that every time I watch them play, they seem like a house of cards that’s just waiting to come crashing down, so I pick against them, only to find out that the cards are actually made of steel and that that house is never going to fall down AKA the Eagles are never going to lose. … Heading into Week 13, Hurts has the best passer rating in the NFL in games where his team is tied or trailing in the second half/overtime. When the Eagles are trailing, Hurts turns into Superman: He has 10 touchdown passes and zero interceptions and his QB rating is 136.6. It’s almost like the Eagles LET the other team get a second-half lead because they know it will activate Super Hurts.
“On the flip side, the one quarterback you don’t want on your team if you find yourself trailing in the second half is Brock Purdy. The 49ers QB has the lowest QB rating in the NFL this year when his team is tied or trailing in the second half. Basically, if this is a tight game in the second half, you feel a lot better about having Hurts over Purdy. The good news for the 49ers is that I don’t think Purdy will be playing from behind in the second half.
“This truly feels like a coin flip game, and I’m rolling with the 49ers for two reasons: First, they’re going to be desperate. If they want to have any shot at the No. 1 overall seed, they have to win this game. Second, the 49ers will be coming into this game on 10 days of rest, which I think is a huge advantage in a game like this.
“The 49ers are 5-0 in their past five games where they’ve had at least nine days of rest and they’ve won those five games by an average of 17.8 points per game. Also, I’m taking the Niners because at this point, I think Eagles fans actually like it more when I pick against their team.” — CBS Sports NFL writer John Breech on why he likes the 49ers to win and cover against the Eagles on Sunday. To see all of his Week 13 picks, click here
Chiefs at Packers
Time: Sunday, 8:20 p.m. ET (NBC), stream on fubo (try for free)
Open: Chiefs -7, O/U 42.5
Featured Game | Green Bay Packers vs. Kansas City Chiefs
R.J. White has consistently crushed his ATS picks and closed out the 2022 season on a remarkable 107-80-6 run on his last 193 against-the-spread and total NFL picks, returning $1,800 for $100 bettors. What makes him the perfect SportsLine expert for this “Sunday Night Football” showdown is that due to White’s strong ATS record specifically in games involving Green Bay. White is 63-25-2 (+3502) on his last 90 against-the-spread picks in Packers games, so you’ll certainly want to see which way he is rolling in Week 13. We can tell you he’s leaning Over the total, but to see his ATS pick you’ll have to head over to SportsLine.
Bengals at Jaguars
Time: Monday, 8:15 p.m. ET (ESPN), stream on fubo (try for free)
Open: Jaguars -7.5, O/U 41.5
Featured Game | Jacksonville Jaguars vs. Cincinnati Bengals
SportsLine NFL expert Mike Tierney has covered the NFL for decades and reported from seven Super Bowls. He is coming off a typically strong 2022 NFL season in which he went 68-54-6, returning $815 to $100 players. Tierney is also an amazing 38-16 on his last 54 picks in games involving the Jaguars, returning $2,073! Naturally, you’ll want to see who he has for this Monday night matchup, especially after Tierney has found a key X-factor that has him backing one side of the spread. We can tell you he’s leaning Under the total, but to read his ATS pick you’ll need to go to SportsLine.