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Vasiliy Lomachenko vs. George Kambosos odds, prediction: Proven boxing expert reveals May 11 fight picks

Former three-division world boxing champion Vasiliy Lomachenko will attempt to become a champion again on Saturday when he faces George Kambosos Jr. for the vacant IBF lightweight title. Their 12-round boxing main event tops the Lomachenko vs. Kambosos fight card (8 p.m. ET) from RAC Arena in Perth, Australia. The title is vacant because it was left behind by former unified lightweight champion Devin Haney, who discarded all four major belts before moving up to junior welterweight. Coincidentally, Lomachenko hasn’t fought since dropping a disputed decision last May against Haney for the unified lightweight title that Haney won by defeating Kambosos. Kambosos is coming off a majority decision victory against Maxi Hughes last July.

Lomachenko is a -650 favorite (risk $650 to win $100), while Kambosos is priced at +450 in the latest Vasiliy Lomachenko vs. George Kambosos Jr. odds. The over/under for total rounds is 10.5, with the Over shaded to -310. Before locking in any George Kombosos Jr. vs. Vasiliy Lomachenko picks, make sure you see the boxing predictions and betting advice from SportsLine expert Brandon Wise

Wise, who is the combat sports editor for CBS Sports, is an experienced boxing and mixed martial arts analyst who has consistently provided winning selections for SportsLine members. For the past four years, he has hit numerous boxing selections in big-time matchups.

For example, in March, Wise called a win in Round 1 for Jake Paul (+200) against Ryan Bourland and also advised SportsLine members to take the Under 1.5 rounds (+120). Both bets connected when Paul scored a knockout toward the end of the first round. Anyone who has followed Wise’s combat sports picks has already seen massive returns.

Now, with Vasiliy Lomachenko vs. George Kambosos Jr. on deck, Wise has studied the matchup from every angle and released confident picks for the fight. You can only see those picks at SportsLine

Vasiliy Lomachenko vs. George Kambosos Jr. preview 

Lomachenko (17-3) is a two-time Olympic gold medalist who is widely considered one of the most prolific amateur boxers in the history of the sport. The 36-year-old Ukrainian has since gone on to become one of the top professional boxers of this generation. In a rarity for boxing, and on the strength of his colossal amateur career, Lomachenko was fast-tracked to a title fight in just his second appearance as a pro and won the vacant WBO featherweight title in his third pro fight with a majority decision over Gary Russell Jr. in June 2014.

In just his 12th professional fight, Lomachenko won a title in a third weight class, but he became something of a polarizing star for the sport. Although he had become one of boxing’s dominant champions, it often appeared as though he purposely exhibited a risk-averse style that involved him doing the minimum necessary to defeat overmatched opponents. 

His shield of invincibility was shattered when Teofimo Lopez took Lomachenko’s two major lightweight belts with a dominant unanimous decision in October 2020. However, in just his first defense, Lopez was defeated by Kambosos, an upset that many considered an even bigger one than Lopez over Lomachenko.

Kambosos (21-2) is a straight-ahead brawler who is known for maximizing his somewhat limited natural talent with grit and determination, along with a touch of good fortune. To illustrate the latter, his upset of Lopez was his third consecutive split-decision victory.

Kambosos saw his first defense result in a lopsided decision loss to Haney in June 2022, and a contracted rematch four months later netted the same outcome. Haney proceeded to take a razor-thin decision in May of last year against Lomachenko, though many observers believed the Ukrainian deserved to get his hand raised. See who to back here

How to make Vasiliy Lomachenko vs. George Kambosos Jr. picks

We can share that Kahn likes the Over 10.5 rounds. He’s also locked in a method-of-victory prop and a confident money-line pick. You can only see his picks and analysis at SportsLine

Who wins George Kambosos Jr. vs. Vasiliy Lomachenko, and which prop is a must-back? Visit SportsLine now to see Brandon Wise’s best bets for Saturday, all from the boxing expert who nailed Jake Paul’s first-round knockout in March, and find out.

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