Alabama vs. Ole Miss odds, line, spread: 2021 college football picks, SEC on CBS predictions from proven model

It’s a battle of unbeaten teams on Saturday afternoon when the No. 1 Alabama Crimson Tide host the 12th-ranked Ole Miss Rebels in the SEC on CBS matchup at Bryant-Denny Stadium. The Crimson Tide are 4-0 and Ole Miss has dominated all three of its games, but Alabama has won five-straight meetings and is 52-10-2 all-time against the Rebels. Both teams have been lighting up scoreboards in the early going, with the Rebels scoring an FBS-high 52.6 points per game and the Tide ranking fourth at 46.5. This matchup should play a big role in determining the Heisman Trophy winner, as well. Quarterbacks Bryce Young of Alabama and the Rebels’ Matt Corral are the early +180 co-favorites for the award, according to Caesars Sportsbook.   

Kickoff is set for 3:30 p.m. ET in Tuscaloosa, Ala. The Crimson Tide are the 14.5-point favorites in the latest Ole Miss vs. Alabama odds from Caesars Sportsbook, while the over-under for total points scored is 79. Before locking in any Alabama vs. Ole Miss picks, make sure to check out the college football predictions and analysis from the proven SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,300 for $100 players on its top-rated college football picks against the spread. After going a sizzling 9-3 in Week 4, It also enters Week 5 of the 2021 season on a 81-61 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has locked in on Alabama vs. Ole Miss and just revealed its picks and predictions. You can head to SportsLine now to see the model’s picks. Here are the betting lines and trends for Ole Miss vs. Alabama:  

  • Mississippi vs. Alabama: Crimson Tide -14.5 
  • Mississippi vs. Alabama over-under: 79 points 
  • Mississippi vs. Alabama moneyline: Rebels +450, Crimson Tide -650 
  • MISS: The Rebels are 5-0 ATS in their last five as road underdogs
  • ALA: The Crimson Tide are 13-8 ATS as home favorites since 2018

Featured Game | Alabama Crimson Tide vs. Ole Miss Rebels

Why Alabama can cover

The Crimson Tide have already faced a test this season, beating current No. 10 Florida 31-29 on Sept. 18. Young has passed for 1,124 yards and 15 touchdowns, with one interception. He is completing more than 72 percent of his passes and has been sacked six times. The sophomore has a huge downfield threat in Jameson Williams, who averages 24.9 yards per catch and has three touchdowns. John Metchie III leads the team with 24 catches, and tight ends Jahleel Billingsley and Cameron Latu have six touchdowns combined. Billingsley averages 21.8 yards per reception. 

Alabama also averages 115.8 yards per game on the ground (21st), with three backs over 100 yards, led by Brian Robinson Jr. (208, two TDs). They will face a Rebels defense that ranks outside the nation’s top-50 in total yardage (344.7 per game, 59th), passing (208.5, 53rd) and rushing (136, 61st) and allows 20.7 points per game (50th). Meanwhile, the Tide defense is 17th in total yards allowed (283.8) and has seven takeaways, including interceptions by six different players. The Tide have scored at least 59 points in four straight meetings, winning by an average of 40.         

Why the Ole Miss can cover

Ole Miss hasn’t had much success against the Tide, but the Rebels have never had a balanced offense like this. They are 6-2 against the spread in their last eight meetings in Alabama and have scored 79 points over the past two matchups. This year’s offense leads FBS in total yards (635.3 per game) and and is outscoring its opponents by 32 per contest. Ole Miss also ranks fourth in rushing, putting up 298.7 yards. The difference could be Corral, who has 997 passing yards, with nine scoring passes and no picks. He also has 158 rushing yards and five TDs.          

Corral is one of three Rebels with more than 150 rushing yards, with Jerrion Ealy leading the way with 188 (6.1 per carry) and Henry Parrish Jr. right behind at 176 (7.0 per rush). Eary also is a receiving threat, and Corral has a strong rapport with big-play wideouts Dontario Drummond (339 yards, four TDs) and Jonathan Mingo (19.3 per catch, three TDs). The Tide defense has strong numbers, but Florida outgained Bama by more than 100 yards (439-331) and ran for 244. Sam Williams has four sacks for the Rebels and could make things uncomfortable for Young.        

How to make Mississippi vs. Alabama picks

The model has simulated the Alabama vs. Mississippi matchup 10,000 times, and the results are in. The model is projecting under on the point total, suggesting the teams won’t even combine for 74 points. It also has generated a point-spread pick that is hitting in nearly 60 percent of simulations. You can only get the model’s Alabama vs. Ole Miss picks at SportsLine

So who wins the Mississippi vs. Alabama matchup on Saturday? And which side of the spread is hitting almost 60 percent of the time? Visit SportsLine right now to see which side of the Alabama vs. Mississippi spread to back Saturday, all from the advanced model on an 81-61 run on its top-rated college football picks, and find out.

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