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Charlotte vs. FIU odds, point spread: 2021 college football picks, Week 6 predictions from model on 12-4 run

One of this week’s earliest college football matchups will feature two teams on opposite ends of the spectrum in the Conference USA standings. FIU (1-4) will host Charlotte (3-2) on Friday at Riccardo Silva Stadium. While the 49ers have been much more successful than the Panthers this year, oddsmakers still expect a close matchup. 

Kickoff is set for 7 p.m. ET. The 49ers are 3.5-point favorites in the latest Charlotte vs. FIU odds from Caesars Sportsbook, while the over-under for total points scored is 60. Before locking in any Charlotte vs. FIU picks or college football predictions, you need to see what the proven SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It also enters Week 6 of the 2021 season on a 12-4 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Charlotte vs. FIU and just revealed its CFB picks and predictions. You can visit SportsLine now to see all of the model’s college football picks. Here are the college football odds and betting lines for FIU vs. Charlotte:

  • Charlotte vs. FIU spread: Charlotte -3.5 
  • Charlotte vs. FIU over-under: 60 points  
  • Charlotte vs. FIU money line: Charlotte -175, FIU +150 
  • CLT: The total has gone under in four of Charlotte’s last five games 
  • FIU: The Panthers are 5-0 straight up in their previous five games against the 49ers

Featured Game | FIU Panthers vs. Charlotte 49ers

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Why Charlotte can cover

The 49ers are one of the two undefeated teams in Conference USA East. They edged out MTSU for their first conference win of the year earlier this season. Charlotte’s passing attack could be vital to taking down a rival that’s dominated this matchup in recent years. 

Charlotte’s senior signal-caller Chris Reynolds has thrown for 1,115 yards, 11 touchdowns, and three interceptions this season. Division-II transfer Grant DuBose has a lot to do with that production. He’s among the NCAA’s leaders in receptions (24) and has tallied 393 receiving yards to go along with four touchdowns. FIU has given up more than 300 passing yards in three straight games, so the 49ers could run away with a win here.

Why FIU can cover

FIU is off to a slow start to the 2021 season, but has history on its side. The Panthers have won five straight games against the 49ers. Their balanced offense makes them a threat to defend their home field in a shootout.

FIU’s Max Bortenschlager ranks 17th in the NCAA in passing yards. Tyrese Chambers and Bryce Singleton have eclipsed 400 receiving yards for the Panthers, but they can also depend on a sturdy ground game. D’Vonte Price has racked up 411 rushing yards and six touchdowns on the ground. He’ll face a Charlotte defense that gave up 257 rushing yards and two touchdowns to IllinoisChase Brown last week. If the Panthers can establish the ground game early, they can upset Charlotte. 

How to make Charlotte vs. FIU picks

SportsLine’s model is leaning over on the point total. It’s projecting the two teams to combine for 61 points. It also has generated an against-the-spread pick that cashes in well over 50 percent of simulations. You can only get the model’s Charlotte vs. FIU ATS pick at SportsLine.

So who wins Charlotte vs. FIU? And which side of the spread cashes well over 50 percent of the time? Visit SportsLine now to see which side of the FIU vs. Charlotte spread to back, all from the advanced model that is up almost $3,300 on its top-rated college football spread picks, and find out.

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