College football odds, lines, bets, predictions for Week 8, 2021: Computer model picks Notre Dame, Indiana


The Week 8 college football schedule brings another extended lineup of action. No. 14 Coastal Carolina and Appalachian State (+3.5) kick the week off on Wednesday evening. There are then four games on Thursday and Friday leading into another full Saturday. The Week 8 college football odds from Caesars Sportsbook list No. 13 Ole Miss at -10.5 against LSU in the 3:30 p.m. ET SEC on CBS matchup on Saturday.

Other Week 8 college football lines for games involving contenders include No. 4 Alabama (-27.5) against Tennessee, No. 2 Cincinnati (-28) against Navy and No. 6 Michigan (-21.5) against Northwestern. Which college football spreads should you be targeting for your bets this week? Before making any Week 8 college football picks on those games or others, be sure to see the latest college football predictions and betting advice from SportsLine’s proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 8 of the 2021 season on a 22-9 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Week 8 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top Week 8 college football predictions

One of the top college football picks the model is recommending for Week 8: No. 13 Notre Dame covers (-7) against USC at 7:30 p.m. ET on Saturday. The Trojans have lost three of their last five games by at least 14 points. Notre Dame, meanwhile, has covered in three of its last four games. 

The simulations show Notre Dame running back Kyren Williams accounting for close to 100 yards from scrimmage as the Irish cover almost 60 percent of the time. This game also reaches the 60-point plateau in the projections, making the over (58) the clear value play. 

Another one of the college football predictions from the model: Indiana (+19) stays within the three-score spread against No. 5 Ohio State in a 7:30 p.m. ET matchup on Saturday. The Hoosiers don’t look great on paper with a 2-4 overall record and a 0-5 mark against the spread when playing FBS competition. But they’re hoping to get star quarterback Michael Penix Jr. (shoulder) back. 

And they’ve kept it competitive against top-10 competition. They lost by just five points to Michigan State last week and kept it within two scores against Cincinnati earlier this season. The model projects this to be a 13-point game as the Hoosiers cover in well over 50 percent of simulations. There’s also plenty of value on the under (60), as that hits more than 60 percent of the time, making for a great parlay opportunity. 

How to make Week 8 college football picks 

The model has also made the call on who wins and covers in every other game on the Week 8 college football schedule, and it’s calling for a top-10 team to go down hard. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence? And which top-10 squad goes down hard? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $3,700 in profit over the past five-plus seasons, and find out.

Week 8 college football odds (via Caesars)

Here are the college football lines for some of Week 8’s most notable matchups:

Wednesday, Oct. 20

Coastal Carolina vs. Appalachian State (+3.5, 59.5)

Featured Game | Appalachian State Mountaineers vs. Coastal Carolina Chanticleers

Thursday, Oct. 21

Louisiana vs. Arkansas State (+17, 66.5)

Featured Game | Arkansas State Red Wolves vs. Louisiana Ragin’ Cajuns

Tulane vs. SMU (-14, 70)

Featured Game | SMU Mustangs vs. Tulane Green Wave

FAU vs. Charlotte (+5.5, 54.5)

Featured Game | Charlotte 49ers vs. Florida Atlantic Owls

San Jose State vs. UNLV (+4.5, 46.5)

Featured Game | UNLV Rebels vs. San Jose State Spartans

Friday, Oct. 22

MTSU vs. UConn (+15, 54)

Featured Game | Connecticut Huskies vs. Middle Tenn. Blue Raiders

Memphis vs. UCF (-2.5, 64.5)

Featured Game | UCF Knights vs. Memphis Tigers

Colorado State vs. Utah State (+3, 55)

Featured Game | Utah State Aggies vs. Colorado State Rams

Washington vs. Arizona (+15.5, 44.5)

Featured Game | Arizona Wildcats vs. Washington Huskies

Saturday, Oct. 23

Wake Forest vs. Army (+3, 52)

Featured Game | Army West Point Black Knights vs. Wake Forest Demon Deacons

Michigan vs. Northwestern (+21.5, 50)

Featured Game | Michigan Wolverines vs. Northwestern Wildcats

Cincinnati vs. Navy (+28, 50.5)

Featured Game | Navy Midshipmen vs. Cincinnati Bearcats

Wake Forest vs. Army (+3, 52)

Featured Game | Army West Point Black Knights vs. Wake Forest Demon Deacons

Penn State vs. Illinois (+23.5, 46.5)

Featured Game | Penn State Nittany Lions vs. Illinois Fighting Illini

Oklahoma vs. Kansas (+38, 67.5)

Wisconsin vs. Purdue (+3, 38)

Featured Game | Purdue Boilermakers vs. Wisconsin Badgers

Clemson vs. Pittsburgh (-3.5, 47)

Featured Game | Pittsburgh Panthers vs. Clemson Tigers

Oklahoma State vs. Iowa State (-7, 47)

Featured Game | Iowa State Cyclones vs. Oklahoma State Cowboys

Ole Miss vs. LSU (+10.5, 76)

Featured Game | Ole Miss Rebels vs. LSU Tigers

Oregon vs. UCLA (-1.5, 58.5)

Featured Game | UCLA Bruins vs. Oregon Ducks

UTSA vs. Louisiana Tech (+6, 58)

Featured Game | Louisiana Tech Bulldogs vs. UTSA Roadrunners

San Diego State vs. Air Force (-4, 41)

Featured Game | Air Force Falcons vs. San Diego State Aztecs

Ohio State vs. Indiana (+19, 60)

Featured Game | Indiana Hoosiers vs. Ohio State Buckeyes

NC State vs. Miami (FL) (+3.5, 53)

Featured Game | Miami (FL) Hurricanes vs. NC State Wolfpack

Texas A&M vs. South Carolina (+21, 44.5)

Featured Game | Texas A&M Aggies vs. South Carolina Gamecocks

USC vs. Notre Dame (-7, 58)

Featured Game | Notre Dame Fighting Irish vs. USC Trojans





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