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College football picks, odds, 2021 Championship Week bets from top expert: This three-leg parlay returns 6-1

Championship Week has arrived in college football as the action unfolds Friday and Saturday. Ten conferences will crown a champion. At least four of those games will have major implications for the College Football Playoff field. Bettors will keep that in mind as they evaluate matchups like No. 1 Georgia vs. No. 3 Alabama (4 p.m. ET, CBS) on Saturday. Caesars Sportsbook lists the Bulldogs at -6.5 in the latest college football odds for Championship Week.

No. 5 Oklahoma State will try to squeeze into the playoff field, but it needs to knock off No. 9 Baylor (+5.5) in the Big 12 Championship Game to have a shot. Other college football lines of note for Championship Week include No. 2 Michigan at -11 against No. 13 Iowa in the Big Ten Championship Game and No. 4 Cincinnati at -10.5 against No. 21 Houston in the AAC title matchup. Which games should you target for college football bets and parlays? Before locking in any college football picks on those games or others, be sure to see the top Championship Week college football expert picks, predictions and best bets from Barrett Sallee.

Sallee is a true insider — a CBS Sports analyst, SiriusXM host, Heisman voter and consistently one of the top CBS Sports experts picking games against the spread — and his best bets have helped bring in huge returns. He debuted with SportsLine in 2017 and has delivered in a big way on his college football picks

Over the past two-plus years, he is 98-78 in his popular best bets column at SportsLine. Anybody who has been following him is way up.

Now, he has turned his attention to the Championship Week college football odds from Caesars and is sharing his top three best bets over at SportsLine. If you parlay them together, you could be looking at a return of around 6-1. Get his top college football picks now

Top Championship Week college football expert predictions

One of Sallee’s top college football picks for Championship Week: He’s backing No. 21 Houston (+10.5) against No. 4 Cincinnati in the 2021 AAC Championship Game on Saturday at 4 p.m. ET.

Since opening the season with a loss to Texas Tech, the Cougars have gone unbeaten. They haven’t been the underdogs very frequently, but they’ve stayed within the spread both times when they were, including pulling off outright upset wins against Tulsa and SMU

Cincinnati, on the cusp of possibly being the first Group of Five team to make the playoffs, has a lot to lose in this one. The Cougars should be able to play loose and at least keep this one competitive enough to cover. 

“The Cougars have won 11 straight, quarterback Clayton Tune has settled in nicely and they’re 2-0 against the spread as 8.5 to 12.5 underdogs,” Sallee told SportsLine. “Plus, it’s still hard for me to trust a Bearcats team that, other than the win over SMU two weeks ago, has been a little sketchy in most of their games in the second half of the season.”

Featured Game | Cincinnati Bearcats vs. Houston Cougars

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How to make Championship Week college football picks 

Sallee has also found two other college football picks he’s high on, including a play on a team set to roll to an easy cover that “will impress members of the College Football Playoff selection committee.” You can only see his picks at SportsLine.

What are the best bets for Championship Week in college football? And which college football picks need to be part of your parlays? Visit SportsLine now to see Barrett Sallee’s college football best bets, all from one of the top analysts in the nation who has crushed his picks for SportsLine.

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