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Illinois vs. Charlotte odds, line: 2021 college football picks, Week 5 predictions from proven computer model

The Charlotte 49ers will take on the Illinois Fighting Illini at noon ET on Saturday at Memorial Stadium. Illinois is 1-4 overall and 1-2 at home, while the 49ers are 3-1 overall and 0-1 on the road. Illinois brings a 3-2 record against the spread in this matchup, while Charlotte is 1-1 ATS against FBS competition.

The Fighting Illini are favored by 9.5 points in the latest Illinois vs. Charlotte odds from Caesars Sportsbook, and the over-under is set at 54.5. Before entering any Charlotte vs. Illinois picks, you’ll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,300 for $100 players on its top-rated college football picks against the spread. After going a sizzling 9-3 in Week 4, It also enters Week 5 of the 2021 season on an 81-61 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Illinois vs. Charlotte. You can head to SportsLine to see its picks. Here are several college football odds for Charlotte vs. Illinois:

  • Illinois vs. Charlotte spread: Illinois -9.5
  • Illinois vs. Charlotte over-under: 54 points

Featured Game | Illinois Fighting Illini vs. Charlotte 49ers

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What you need to know about Illinois

On Saturday, the Fighting Illini were within a late touchdown of stealing the victory, but they ultimately fell against the Purdue Boilermakers 13-9. It was the fourth straight loss for Illinois after Bret Bielema’s team opened the season with an upset of Nebraska. The Illini, however, have largely been competitive, with four of their five games being decided by just one score. 

Brandon Peters was back under center against Purdue after missing time due to an injury. His numbers, however, haven’t been as impressive as backup Artur Sitkowski. Running back Joshua McCray leads the team with 265 yards on the ground, while Isaiah Williams has 25 catches for 251 yards. 

What you need to know about Charlotte

Meanwhile, Charlotte edge out MTSU 42-39 last Friday. Quarterback Chris Reynolds had a stellar game for Charlotte as he passed for four TDs and 339 yards on 36 attempts in addition to rushing for one TD and 32 yards. Reynolds has thrown for 924 yards, nine touchdowns and just two interceptions this season. He’s also the team’s third-leading rusher with 143 yards on the ground.

Charlotte has already knocked off a Power Five team (Duke), while Illinois has a loss on its resume against a Conference USA team (UTSA), so Will Healy’s 49ers should be confident they can pull off the upset on the road. 

How to make Charlotte vs. Illinois picks

The model has simulated Illinois vs. Charlotte 10,000 times and the results are in. The model is leaning over on the total, and it’s also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Illinois vs. Charlotte? And which side of the spread is a must-back? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks

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