MLB DFS: Top Red Sox vs. Astros DraftKings, FanDuel daily Fantasy baseball picks, strategy for Oct. 22, 2021

After struggling in Games 2 and 3 for the American League Championship Series, the Houston Astros scored nine runs in each of the last two ALCS games. One of the players that has keyed the offensive turnaround has been left fielder Michael Brantley. In Game 4, he got two late hits, including a ninth inning double that scored three as part of a 9-2 win. He followed that up by getting on base twice and hitting an RBI single in the seventh inning of Game 5.

Brantley has scored the 13th-most Fantasy points in the American League during the postseason on sites like FanDuel and DraftKings, and will need to step up again if Houston wants to close out the series on Friday. Should Brantley be a part of your MLB DFS strategy for Game 6 of Red Sox vs. Astros? Or should you look elsewhere in the MLB DFS player pool for value? Before finalizing your MLB DFS picks for Friday, be sure to check out the MLB DFS advice, strategy and projections from SportsLine daily Fantasy expert Mike McClure.

McClure is a daily Fantasy pro who has won almost $2 million in his career. And when it comes to daily Fantasy baseball, McClure is at his best. Recognized in the book “Fantasy Football (and Baseball) for Smart People: How to Turn Your Hobby into a Fortune” as a top MLB DFS player, McClure’s proprietary projection model simulates each game 10,000 times, taking factors such as matchups and recent results into account. This allows him to find the best values on every site.

On Thursday, McClure listed Dodgers second baseman Trea Turner among his top MLB DFS picks on FanDuel and DraftKings. The result: Turner went 3-for-4 from the plate with a run and an RBI, which returned 15 points on DraftKings and 18.7 points on FanDuel. Anybody that included him in their lineups was well on the way to a profitable day.

Now, with the MLB playoffs 2021 continuing on Friday, October 22, McClure has locked in his top MLB daily Fantasy picks. Head to SportsLine now to see them

McClure’s top MLB DFS picks for Friday, October 22

One of McClure’s top MLB DFS picks for Friday is Red Sox third baseman Rafael Devers, who is listed at $5,000 on DraftKings and $9,500 on FanDuel. Devers has produced the American League’s second-highest Fantasy points total during the 2021 MLB playoffs, and was responsible for Boston’s only run of the night in Game 5, when he hit a seventh inning home run. 

Devers doesn’t have much of a sample size when it comes to his meetings with Houston starting pitcher Luis Garcia, but he’ll certainly be one of the players Boston is counting on to extend the series. Against right-handed pitching in 2021, Devers hit 32 home runs and finished with 85 RBIs during the regular season. He’s currently on a nine-game playoff hitting streak, and he’s scored at least a run in each of those games. Lock him in your MLB DFS lineups and look for a big return against Houston on Friday. 

Another key in McClure’s optimal MLB DFS strategy includes stacking Devers with Red Sox outfielder Kyle Schwarber ($4,700 on DraftKings and $6,500 on FanDuel). In Game 3 of the ALCS, Schwarber got things going for Boston on offense with a second inning grand slam en route to a 12-3 win.

Schwarber has never faced Garcia, but that could work to his advantage. Garcia hasn’t been sharp against leadoff hitters this season, and in a must-win scenario, Schwarber should be aggressive and try to get things cooking for Boston. Garcia incorporates a mix of power and breaking-ball pitches in his repertoire, and against such pitchers, Schwarber had batting splits of .269/.333/.487 during the regular season.

How to set your MLB DFS lineups for Friday, October 22

McClure is also targeting an undervalued player who is set to explode for huge numbers on Friday. The stars are aligning for him to return tournament-winning value and he comes at a price that won’t break the bank. You can only see who it is here.

So what are the top MLB DFS picks for Friday? Visit SportsLine now to see DFS millionaire Mike McClure’s complete player pool and picks for FanDuel and DraftKings, and cash in big on MLB DFS.

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