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Panthers vs. Vikings odds, line, spread: 2021 NFL picks, Week 6 predictions from proven computer model

The Minnesota Vikings will take on the Carolina Panthers at 1 p.m. ET on Sunday at Bank of America Stadium. Carolina is 3-2 overall and 2-1 at home, while the Vikings are 2-3 overall and 0-2 on the road. The Vikings beat the Lions last week, 19-17. The Panthers lost to the Vikings, 21-18. 

The Vikings have won three of the last four matchups between the teams. Minnesota is favored by 2.5 points in the latest Panthers vs. Vikings odds from Caesars Sportsbook, and the over-under is set at 45.5. Before entering any Vikings vs. Panthers picks, you’ll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 6 of the 2021 season on an incredible 125-83 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Panthers vs. Vikings. You can head to SportsLine to see its picks. Here are several NFL betting lines for Vikings vs. Panthers:

  • Panthers vs. Vikings spread: Vikings -25.
  • Panthers vs. Vikings over-under: 45.5 points

Featured Game | Carolina Panthers vs. Minnesota Vikings

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What you need to know about the Panthers

The Panthers squandered a 12-point lead on their loss to the Eagles. Philadelphia scored 15 of the game’s final 18 points. Sam Darnold threw three interceptions in the defeat. He was sacked three times and passed for 177 yards with one TD. 

The Panthers have lost both of their games without Christian McCaffrey (hamstring), and he will not play against Minnesota. Chuba Hubbard rushed for 101 yards and had five receptions in Week 6. D.J. Moore has five-plus catches in his last eight games. 

What you need to know about the Vikings

Greg Joseph’s 54-yard field goal as time expired booted Minnesota to its Week 5 win over Detroit. He made four field goals, including a career-best of 55 yards. Alexander Mattison had a career-high seven catches, 153 scrimmage yards (113 rushing) and a TD catch. He started in place of an Injured Dalvin Cook (ankle), who is not on the injury report for Week 6. 

Justin Jefferson had seven receptions for 124 yards last week. He has nine games with 100-plus receiving yards since 2020, second-most in the NFL. Adam Thielen has nine receiving TDs in his last nine road games. 

How to make Panthers vs. Vikings picks

The model has simulated Panthers vs. Vikings 10,000 times and the results are in. It is leaning over on the total, and it also says one side of the spread has all the value. You can only see the pick at SportsLine.

So who wins Panthers vs. Vikings? And which side of the spread has all the value? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.

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