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College football odds, lines, bets, top predictions for Week 13, 2021: Model picks Oklahoma State, Oregon

The Week 13 college football schedule brings us matchups between some of the top teams in the country. But not all rivalries are evenly-matched. In one the largest of the Week 13 college football spreads at Caesars Sportsbook, Georgia is favored by 35 at Georgia Tech. The Bulldogs are undefeated, No. 1 in the country and they’ve covered huge spreads all season, going 7-3 ATS. The Yellow Jackets, on the other hand, are 3-8 and coming off a 55-0 loss to Notre Dame. 

Other Week 13 college football odds of note include No. 3 Alabama (-20) vs. Auburn in the 2021 Iron Bowl (3:30 p.m. ET, CBS) and No. 2 Ohio State (-8) against No. 5 Michigan. Which college football lines should you target during rivalry week? Before making any Week 13 college football picks on those games or others, be sure to see the latest college football predictions and betting advice from SportsLine’s proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Week 13 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top Week 13 college football predictions

One of the top college football picks the model is recommending for Week 13: No. 7 Oklahoma State (-3.5) covers against No. 10 Oklahoma in the 2021 Bedlam Series rivalry matchup at 7:30 p.m. ET on Saturday. Oklahoma has the overwhelming advantage in total and recent history on its side with a 90-18 record in the series and wins in the previous six matchups.

In this matchup on Saturday night, Oklahoma State can finally claim victory in a game it has sorely wanted to win for years. After years of not being able to match up with the Sooners’ high-octane offense, the Pokes might finally have a unit to match. Oklahoma State’s defense ranks fourth in the nation in yards per carry allowed and 14th in yards per pass attempt allowed. 

SportsLine’s model has Oklahoma State winning and covering the spread in more than 60 percent of simulations, making it a top pick for rivalry week college football bets. The point total sits at 49.5, and SportsLine’s simulations have that going over well over 50 percent of the time.

Another one of the college football predictions from the model: No.11  Oregon (-7) takes care of business against Oregon State in a 3:30 p.m. ET matchup on Saturday. The Ducks are coming off a 38-7 stomping at the hands of Utah that likely eliminated Oregon from College Football Playoff contention. But the model does not think the Ducks are in for a letdown.

In simulations from SportsLine’s model, the Ducks cover that seven-point spread almost 60 percent of the time. The under 60.5 also hits at about the same rate. The model projects a nice game for Oregon quarterback Anthony Brown, and that’s usually enough for Oregon to take home the win on top of another sound defensive performance.

How to make Week 13 college football picks 

The model has also made the call on who wins and covers in every other game on the Week 13 college football schedule, and it’s also calling for a top College Football Playoff contender to get a huge scare from a big underdog. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence? And which underdog do you need to jump on now? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $3,700 in profit over the past five-plus seasons, and find out.

Week 13 college football odds (via Caesars)

Here are the college football lines for some of Week 13’s most notable matchups:

Friday, Nov. 26

Boise State vs. San Diego State (+2.5, 44)

Featured Game | San Diego State Aztecs vs. Boise State Broncos

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Iowa vs. Nebraska (-3.5, 44.5)

Featured Game | Nebraska Cornhuskers vs. Iowa Hawkeyes

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Missouri vs. Arkansas (-14, 62.5)

Featured Game | Arkansas Razorbacks vs. Missouri Tigers

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Cincinnati vs. East Carolina (+14, 58)

Featured Game | East Carolina Pirates vs. Cincinnati Bearcats

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Colorado vs. Utah (-24, 52.5)

Featured Game | Utah Utes vs. Colorado Buffaloes

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UNC vs. NC State (-7, 63)

Featured Game | NC State Wolfpack vs. North Carolina Tar Heels

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Saturday, Nov. 27

Wake Forest vs. Boston College (+5, 64.5)

Featured Game | Boston College Eagles vs. Wake Forest Demon Deacons

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Houston vs. UConn (+32.5, 57.5)

Featured Game | Connecticut Huskies vs. Houston Cougars

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Georgia vs. Georgia Tech (+35, 54.5)

Ohio State vs. Michigan (+8, 64)

Featured Game | Michigan Wolverines vs. Ohio State Buckeyes

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Texas Tech vs. Baylor (-14, 52)

Featured Game | Baylor Bears vs. Texas Tech Red Raiders

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UTSA vs. North Texas (+12, 59.5)

Featured Game | North Texas Mean Green vs. UTSA Roadrunners

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Penn State vs. Michigan State (-1.5, 52.5)

Featured Game | Michigan State Spartans vs. Penn State Nittany Lions

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Oregon State vs. Oregon (-7, 61)

Featured Game | Oregon Ducks vs. Oregon State Beavers

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Alabama vs. Auburn (+19.5, 55)

Featured Game | Auburn Tigers vs. Alabama Crimson Tide

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Wisconsin vs. Minnesota (+6.5, 39)

Featured Game | Minnesota Golden Gophers vs. Wisconsin Badgers

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Texas A&M vs. LSU (+6.5, 45.5)

Latest Odds: LSU Tigers +6.5

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Pittsburgh vs. Syracuse (+11, 58.5)

Featured Game | Syracuse Orange vs. Pittsburgh Panthers

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Oklahoma vs. Oklahoma State (-3.5, 51.5)

Featured Game | Oklahoma State Cowboys vs. Oklahoma Sooners

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Notre Dame vs. Stanford (+17, 52.5)

Featured Game | Stanford Cardinal vs. Notre Dame Fighting Irish

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BYU vs. USC (+7, 64)

Featured Game | USC Trojans vs. BYU Cougars

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